Table 1: Average time course for structural and physiological adaptations to exercise training in horses. Adaptation Time Course Increase in VO2MAX 1 - 2 weeks Increase in plasma volume 1 - 2 weeks Improved sweating response 1 - 2 weeks Increase in red blood cells & haemoglobin 2 - 4 months Increase in muscle capillaries 3 - 6 months Increase in muscle mitochondria 4 - 6 months Increase in muscle aerobic enzymes 4 - 6 months Increase in bone density* 4 - 6 months Strengthening of tendons and ligaments* 4 - 6 months *Available research on training adaptations of supporting structures is limited.